Abstract
Hyaluronic acid (HA)-based injectable fillers three-dimensionally restore the natural contours of the lips and perioral area, thereby reducing some signs of aging lips. To evaluate the short-term aesthetic impact of treatment with the HA dermal filler Juvéderm® VOLBELLA® with Lidocaine, formulated utilizing VYCROSS™ technology, for enhancement or correction of asymmetry of the lips, evaluated using a patient-centric approach. Sixty-two subjects were enrolled in this study, conducted at two sites in Germany. Primary endpoints were satisfaction with improvement, look and feel of the lips, assessed by subject and physician at first visit and 4 weeks post-treatment. Immediately after injection at first visit, 83.6% of subjects were Extremely Satisfied, Very Satisfied or Satisfied with improvement in the lips, which increased to 94.1% and 93.0% of subjects with/without top-up treatment at follow-up, respectively. After injection at first visit, 61.7% of subjects rated the look and feel of their lips as Extremely Natural or Very Natural, which increased to 75.0% and 93.0% of subjects with/without top-up treatment, respectively. The HA dermal filler was associated with minimal discomfort, bruising or swelling of the lips; almost two-thirds of subjects (62%) returned to social engagements on the same day. The high degree of subject satisfaction with aesthetic improvement in the lips, as well as the natural look and feel, indicates that this HA dermal filler represents an effective treatment option for patients requiring lip enhancement.
Highlights
BackgroundAs a key aesthetic feature of the face, fullness and definition of the lips are associated with attractiveness, sensuality and youth
Study of a 15 mg/mL Hyaluronic acid (HA) dermal filler with lidocaine in lips W G Philipp-Dormston et al These morphological changes of the lips become an obvious sign of aging
The HA dermal filler in this study was very well accepted as a new treatment option for the lips by both subjects and physicians, with 83.6% of the subjects being Extremely Satisfied, Very Satisfied or Satisfied with the improvement in their lips after the first injection, and the physicians being Extremely Satisfied or Very Satisfied with lip improvement in 100% of the subjects
Summary
BackgroundAs a key aesthetic feature of the face, fullness and definition of the lips are associated with attractiveness, sensuality and youth. The lips are vulnerable to intrinsic and extrinsic factors that can change their appearance over time.. . Study of a 15 mg/mL HA dermal filler with lidocaine in lips W G Philipp-Dormston et al. Study of a 15 mg/mL HA dermal filler with lidocaine in lips W G Philipp-Dormston et al These morphological changes of the lips become an obvious sign of aging. The effects of gravity coupled with loss of lip volume and support cause the upper lip to lengthen and the lip to fall vertically. The Cupid’s bow and vermilion border lose their distinction,[1] and the inability to conceal these signs of aging may be correlated with increased anxiety and depression.[2]
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