Abstract

Human ovarian tumour transplants (AN-LE) are grown in the thymus defective nude mouse mutant (nu/nu BALB/c/A/Bom). Procedures for local irradiation of the tumors with 60Co-radiation are described. An introductory test of the usefulness of these transplants in studies of radiation effects on human tumors is performed by investigation of the time course of regression of AN-LE transplants in 6 mice, following single exposures to 375, 750 1 180, and 1 575 rad, respectively.

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