Abstract
The predictive values of region of interest (ROI) target detection algorithm-based radiomics for endometrial cancer (EC) lymph node metastasis was investigate in this work. 143 patients with EC admitted by hospital were selected as the research objects and divided randomly into a training group (group A) and a test group (group B). They received preoperative pelvic-enhanced magnetic resonance imaging (MRI) scanning. The ROI algorithm was applied to extract features to construct an EC lymph node radiomics model that was compared with a comprehensive prediction model of EC lymph node. The receiver operating characteristic (ROC) curve was employed to evaluate the diagnostic efficiency of the radiomic model and comprehensive predictive model. Results showed that both the radiomics model (area under the curve (AUC) of group A = 0.875 and AUC of group B = 0.882) and comprehensive prediction model (AUC of group A = 0.917 and AUC of group B = 0.893) had good predictive effects, and effect of the latter was markedly better than that of the former. It indicated that radiomics parameters of ROI target detection algorithm were effective markers for preoperative prediction of EC lymph node metastasis, and its comprehensive prediction model could play a guiding role in clinical decision-making.
Highlights
endometrial cancer (EC) is a very common gynecological malignant tumor [1, 2]
magnetic resonance imaging (MRI) Imaging Based on region of interest (ROI) Target Detection Algorithm. e ratio of positive and negative lymph node patients included in the study was generally 1 : 3–1 : 4, which was the best. e research objects in this study were retrieved from the Department of Medical Records and Pathology
MRI shows the depth of myometrial infiltration, which is correlated to tumor grading and lymph node metastasis, so it is associated with prognosis [14]
Summary
EC is a very common gynecological malignant tumor [1, 2]. In developed countries such as the United States, EC is the fourth largest cancer after breast, lung, and colorectal cancer [3]. e incidence of EC in China is increasing year by year, and it is getting younger and younger. EC is a very common gynecological malignant tumor [1, 2] In developed countries such as the United States, EC is the fourth largest cancer after breast, lung, and colorectal cancer [3]. E incidence of EC in China is increasing year by year, and it is getting younger and younger It is still more common in older women and its mortality is increasing, it is being diagnosed among younger and younger women. Myometrial infiltration, pathological grading, and age are the main factors affecting the prognosis, so the clinical treatment decisions are influenced by them to a certain extent [5].
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