Abstract
The aim of this study was to develop a practical route for preparing a fluorine-18 ([ 18F]) labelled ligand ([ 18F] 1) containing [ 18F]fluorobenzene ring by employing the reaction of diphenyliodonium salt with [ 18F]F −. Diphenyliodonium tosylate ( 2) was synthesized from tributylphenylstannyl compound ( 6) with [hydroxy(tosyloxy)iodo]benzene ( 7). Using this method, [ 18F]DAA1106 ([ 18F] 3a), a positron emission tomography ligand for imaging peripheral-type benzodiazepine receptor, was prepared.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
