Abstract
This study aims to determine the consumption effect of Coleus tuberosus flour and crackers rich in resistant starch type 3 to glucose and lipids profiles in diabetic mice. The study was conducted with four treatments (normal mice with AIN 93 diet, diabetic mice with AIN 93 diet, diabetic mice with Coleus tuberosus flour diet, diabetic mice with coleus tuberosus crackers rich in resistant starch type 3). The analysis of blood glucose levels and lipids profile were determined using an enzymatic colorimetric method with a commercial kit. The results showed that the consumption of Coleus tuberosus flour and crackers rich in resistant starch type 3 can improve glucose and lipids profile (total cholesterol, triglycerides, low-density lipoprotein, high-density lipoprotein) in alloxan-induced diabetic mice. The atherogenic index was smaller on the diet treatment of Coleus tuberosus flour rich in resistant starch type 3 and Coleus tuberosus crackers rich in resistant starch type 3 compared to the AIN 93 feed.This study shows that the raw material (Coleus tuberosus flour rich in resistant starch type 3) and Coleus tuberosus crackers that are rich in resistant starch type 3 can potentially be consumed as a functional food to improve glucose and lipid profiles in diabetes mellitus condition.
Highlights
Coleus tuberosus is one vegetable that belongs to the family Lamiaceae and sub family Nepetoideae
The consumption of raw materials namely Coleus tuberosus flour high in resistant starch type 3 (RS3) can control profile lipids on experimental animals suffering from diabetes mellitus
The risk of coronary heart disease is smaller on the diet treatment of Coleus tuberosus flour rich in RS3 and Coleus tuberosus crackers rich in RS3 compared to the standard feed
Summary
Coleus tuberosus is one vegetable that belongs to the family Lamiaceae and sub family Nepetoideae. Coleus tuberosus originated in tropical and sub tropical Asia, Africa and the Pacific Islands. Coleus tuberosus is a small herbaccous plant, 15-30 cm high, with a succulent stem, dark brown tubers produced in clusters[1]. There are some Coleus tuberosus size, shape and color. Coleus tuberosus is a potential food crop as a source of carbohydrate food alternatives and drugs. Coleus tuberosus is included in the Clade 1b which are exploited as food and medicinal uses (diarrhea, gastric pain)[2]
Published Version
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