Abstract

BackgroundThe clinical manifestations of coronavirus disease 2019 (COVID-19) overlap with those of other disorders, especially cardiovascular disease.Case presentationWe herein describe a 58-year-old woman who presented with syncopal episodes and dyspnea on exertion with a left atrial (LA) mass, scheduled for surgical removal and mitral valve replacement. Nearly 3 months later, the patient developed dyspnea, fever, and a sore throat, resulting in hospital admission with suspected COVID-19. During the diagnostic evaluation, a larger LA mass was detected. The mass seemed to be a COVID-19–induced organized thrombus with prosthetic mitral valve malfunction. Resection was, therefore, planned. An immunohistochemistry study revealed a liposarcoma.ConclusionsThe unusual early recurrence of liposarcomas and the misdiagnosis with COVID-19–induced thrombosis are the hallmark of the present case.

Highlights

  • The recent pandemic of coronavirus disease 2019 (COVID-19) has become the most challenging issue worldwide

  • The unusual early recurrence of liposarcomas and the misdiagnosis with COVID-19–induced thrombo‐ sis are the hallmark of the present case

  • A new left atrial (LA) mass was detected within about 3 months after complete surgical resection, which was suspected as a COVID-19–induced thrombus, diagnosed as a dedifferentiated liposarcoma in the postoperative pathological examination

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Summary

Introduction

The recent pandemic of coronavirus disease 2019 (COVID-19) has become the most challenging issue worldwide. Conclusions: The unusual early recurrence of liposarcomas and the misdiagnosis with COVID-19–induced thrombo‐ sis are the hallmark of the present case. The similarities in the presentations of COVID19 and cardiovascular disease have hindered the diagnosis and management of the latter, in patients with prosthetic heart valves [1, 2].

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Conclusion

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