Abstract
Background: Currently we face a significant increase in the new cases of end-stage renal disease in developing countries. Hence it seems vital to work on strategies and reduce its development and progression. Determining the related risk factors can provide insight into achieving these policy-making goals. Therefore, this study was conducted in order to identify risk factors associated with chronic kidney disease in Iranian adult population. Material and Methods: This cross-sectional study was performed in Shiraz, through a random cluster sampling in 819 including 340 male and 479 female adult participants. Body mass indexes, waist circumference, blood pressure and biochemical profile were assessed. We evaluated the prevalence of CKD according to glomerular filtration rate (GFR) as well as possible risk factors. GFR was calculated based on “Chronic Kidney Disease Epidemiology Collaboration” creatinine equation. Result: Mean age of our participants were 43.0± 14.0 years, and 58.5% were female. Our results showed 16.6% of patients with GFR less than 60 mL/min per 1.73. The proportion of participants having hypertension, obesity, high waist circumference, diabetes mellitus and history of cardiovascular disease were 17.3%,19.3%, 35%,9.4% and 5.3 %, respectively. Multiple regression analysis indicated an independent correlation between age, sex, dyslipidemia, and hypertension with CKD. Conclusion: This study indicates that CKD is a substantial health burden in Iranian adult population. Additionally, the results of this study addressed the importance of integrated strategies that aimed to identify, prevent, and treat non-communicable diseases fueling the development of CKD. [GMJ. 2019;8:e935]
Highlights
Recent investigations have indicated a prominent increase in the incidence and prevalence of chronic kidney disease (CKD), especially in developing countries
We evaluated the prevalence of CKD according to the glomerular filtration rate (GFR), as well as possible risk factors associated with it
This study indicates that CKD is a substantial health burden in Iranian adult population
Summary
Recent investigations have indicated a prominent increase in the incidence and prevalence of chronic kidney disease (CKD), especially in developing countries. A newer equation named “Chronic Kidney Disease Epidemiology Collaboration” (CKD-EPI) showed more reliable GFR estimates. It was more efficient in detecting preclinical end-organ changes than those calculated by other equations [6]. Materials and Methods: This cross-sectional study was performed in Shiraz, Southern Iran, through a cluster random sampling technique that involved 819 subjects, including 340 male and 479 female adult participants. Factors such as the body mass index, waist circumference, blood pressure, and biochemical profile were determined.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
