Abstract

Systemic inflammatory activity has turned out to play a key pathogenic role in vascular atherosclerosis, insulin resistance, and type 2 diabetes mellitus (T2DM). Inflammatory biomarkers may therefore be a valuable tool for risk evaluation. Data suggest that High sensitive C reactive protein (hs-CRP) may participate directly in the process of atherogenesis. The analyses were done with 90 type 2 diabetic and 60 non-diabetic individuals. Anthropometric and biochemical parameters were studied to assess the association of hs-CRP with in T2DM. T2DM encompasses-90% of the diabetic subjects, and it is characterized by insulin resistance often accompanied by obesity and dyslipidemia. High sensitive C reactive protein, the golden marker of inflammation was analyzed in diabetic subjects. Serum hs-CRP levels were positively related to anthropometric parameters. Elevated level of hs-CRP in diabetic subjects was observed with insulin resistance and has strong cardio vascular risk marker in these individuals.

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