Abstract

Background and Aims: Severe hypertriglyceridemia (sHTG; fasting triglycerides ≥500 mg/dL) is a causal risk factor for acute pancreatitis. This phase 2 study (NCT03452228) evaluated efficacy and safety of evinacumab, an investigational angiopoietin-like protein 3 inhibitor, in patients with sHTG who had ≥1 prior hospitalization for acute pancreatitis.

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