Abstract
Abstract A one-step high yield synthesis from commercially available starting material is reported for the novel phosphotyrosyl mimetic, N α -Fmoc-4- O -[ O ′, O ″-di- tert -butyl-2-(2-fluoromalonyl)]- l -tyrosine. The conditions employed for this transformation may also be applicable for the direct electrophilic fluorination of other N α -Fmoc-protected amino acids.
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