Abstract
Background Vaccine, as an irreplaceable means in herd immunization, is widely applied in prevention for communicable diseases. However, adverse impacts were frequently incurred by fake or expired vaccines in China. Given the necessity of vaccine anticounterfeiting, blockchain-based transaction platform could be practiced as a solution in addressing the issue; however, most of the available experiments focused on single-chain structured design with inventible limitations. Accordingly, exploration for the effectiveness and feasibility of mixed-chains structured platform for vaccine anticounterfeiting and tracing is essentially required. Methods Both public chain and private chain were inserted in anticounterfeiting and tracing platform designing process, which were subsequently simulated in Ethereum environment. Results By recording different information in public chain and private chain, partial information privacy protection requirements are realized. The transfer identification module realized the function of vaccine quality supervision and solves the problem of EPC label replication. Discussion. Compared with the traditional single-structured design, completeness information could be visited by all stakeholders in double-chain structure, including vaccine suppliers, National Medical Products Administration (NMPA), vaccine purchasers, and the vaccinated. Conclusion Double-chain structured system for vaccine anticounterfeiting and tracing is more effective.
Highlights
Vaccine, as an irreplaceable means in herd immunization, is widely applied in prevention for communicable diseases
Given the necessity of vaccine anticounterfeiting, blockchain-based transaction platform could be practiced as a solution in addressing the issue; most of the available experiments focused on single-chain structured design with inventible limitations
Both public chain and private chain were inserted in anticounterfeiting and tracing platform designing process, which were subsequently simulated in Ethereum environment
Summary
As an irreplaceable means in herd immunization, is widely applied in prevention for communicable diseases. Given the necessity of vaccine anticounterfeiting, blockchain-based transaction platform could be practiced as a solution in addressing the issue; most of the available experiments focused on single-chain structured design with inventible limitations. Exploration for the effectiveness and feasibility of mixed-chains structured platform for vaccine anticounterfeiting and tracing is essentially required. Double-chain structured system for vaccine anticounterfeiting and tracing is more effective. As. Journal of Healthcare Engineering the current supervision system failed in detecting the fake packages as well as vaccine tracing, the novel system could be suggested to improve from aspects of transparency, traceability, and credibility. Based on the key needs proposed by primary health care and population health care system in China, the corresponded requirements for establishing a blockchain-based vaccine anticounterfeiting and traceability system could be summarized as follows:. (2) How to protect the privacy of vaccinators given the requirement of traceable information openness?
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