A novel non-enzymatic glucose electrochemical sensor with high sensitivity and selectivity based on CdIn2O4 nanoparticles on 3D Ni foam substrate

Abstract

Due to the poor conductivity of Fe based, Cu based and Co based electrode materials commonly used in the electrochemical detection of glucose, and the uneven stirring and poor conductivity of the traditional preparation method based on glassy carbon electrode. In order to solve the above problems, in this work, CdIn2O4 with high electrical conductivity was directly grown on three-dimensional (3D) Ni foam to prepare electrode materials for non-enzymatic glucose sensors. CdIn2O4 nanoparticles is prepared from cadmium acetate and indium nitrate hydrate in benzyl alcohol by non-aqueous sol–gel method. The electrocatalytic oxidation performances of CdIn2O4 electrode material for non-enzymatic glucose are studied. The results show that the proposed CdIn2O4 electrode material has good electrochemical properties and sensing performance for glucose detection. The electrochemical response of CdIn2O4 electrode material to glucose is recorded that calibration plot for glucose concentrations ranging from 1.0 μM to 1.0 mM (R 2 = 0.99), a limit detection of 0.08 μM, an excellent sensitivity of 3.2925 mA.mM−1.cm−2, a rapid response time of 1.58 s, a good selectivity and a good long-term stability. These demonstrate the significant potential of CdIn2O4 electrode material based on 3D Ni foam as non-enzymatic glucose sensors, which makes it possible to use it as a practical glucose detector. This work could introduce a new concept of nanoparticles modified electrode material grown directly on 3D Ni foam, thus a simple and reliable electrochemical glucose sensor platform is realized. This study was completed in 2019 in the school of materials and energy, Yunnan University.