A Novel Method of Image Guided Radiation Treatment of Prostate Cancer Using a Quasi-Adaptive Margin and Evidence Based Isocenter Shift

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In our practice, localized prostate cancers are treated by radiation via a combination of Image Guided Radiation Therapy (IGRT) followed by the conventional Intensity Modulated Radiation Therapy (IMRT). The rationale is that in the first phase using IGRT, daily movements of the prostate can be measured. This allows us to predict a “global mean shift”, which defines the positioning of patient for the second phase; and the variance of daily displacements for each patient, which is incorporated into the posterior margin, which we called a “Quasi Adaptive Margin”.