Abstract
A novel hydrogel was prepared by crosslinking hyaluronan with glycol chitosan in aqueous solution using water soluble carbodiimide at nearly neutral pH and room temperature. The products can be easily formulated into injectable gels, various films, membranes and sponges for soft tissue augmentation, viscosupplementation, drug delivery, preventing adhesion of post operation, wound dressing and tissue engineering scaffolds. The said hydrogel has high water adsorption property and biostability. Rheololgical results of the gel showed a soft and viscoelastic structure. FTIR further confirmed the formation of amide bonds between carboxyl groups of hyaluronan and amine groups of glycol chitosan and no N-acylurea and other derivatives were identified.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Materials Science: Materials in Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
