A novel electrochemical sensor based on MoO3 nanobelt-graphene oxide composite for the simultaneous determination of paracetamol and 4-aminophenol

Abstract

This work presents the fabrication of an electrochemical sensor for the simultaneous determination of paracetamol and 4-aminophenol, using a carbon paste electrode modified with MoO3 nanobelt-graphene oxide (MoO3-GO) composite. The electrochemical behavior and performance of the sensor for the electrooxidation of paracetamol and 4-aminophenol were investigated using cyclic voltammetry, electrochemical impedance spectroscopy, and differential pulse voltammetry techniques. The inclusion of MoO3-GO in the carbon paste electrode increased the catalytic performance of the modified electrode towards the oxidation of paracetamol. The MoO3-GO/CPE sensor exhibit linear dynamic ranges 1.0–90.0 μmol L−1 and 1.0–70.0 μmol L−1 with detection limits of 0.39 μmol L−1 and 0.16 μmol L−1 for paracetamol and 4-aminophenol, respectively. The developed sensor was successfully used for the determination of paracetamol and 4-aminophenol. in urine samples with satisfactory results.