Abstract
A) To address the inability of present artificial implants in previous studies by the authors, a functional periodontium was successfully regenerated using a processed allo-tooth implant. In the present study, to induce similar regeneration, the authors have attempted to promote regeneration of periodontal tissue using a collagen-coated hydroxyapatite (HA) implant in a dog model. B)Implants were produced by wrapping hollow cylinders of porous HA (1=10mm, d0=3mm, d1=1mm, porosity=54%) in collagen, and applying a 24-hour cross-linking treatment at 120°C. Ten implants were placed in the extraction sites of five beagle dogs to evaluate their clinical effectiveness. Three months post-operatively, light microscopic analysis was employed to evaluate the regenerated tissue around the implants histopathologically. C) Three months post-operatively, all implants remained firmly attached at their implantation sites. Microscopic analysis revealed periodontal fiber tissue attached to the implants oriented perpendicular to the implant surface in seven cases. Regeneration of the cementum was also observed on the implant surface in eight cases. Such results show that periodontal tissue can be successfully regenerated at extraction sites using collagen-coated hydroxyapatite implants.
Published Version
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