Abstract
A new cocrystal of the Zn(II) coordination molecule and the benzimidazole (bim), [Zn(bim)(SCN)3]-[Hbim] (C10H6N5S3Zn-C7H7N2, cocrystal 1) was directly synthesized at room temperature. X-ray single crystal diffraction analysis showed that cocrystal 1 is extended into a 3D supramolecular network via hydrogen bonding and π⋅⋅⋅π stacking interactions. Information on non-covalent interactions were gathered by calculating the Hirshfeld surface and fingerprint of the crystal stacking of cocrystal 1. Photoluminescence experiments demonstrated that cocrystal 1 not only possessed good solid-state fluorescence performance but also favorable fluorescence characteristics and stability in aqueous solutions. Notably, cocrystal 1 exhibited excellent anti-interference properties, high sensitivity, high fluorescence enhancement, and low limit of detection (LOD: 59.8 μM) against triethylamine (TEA) in aqueous medium via the “Turn-On” effect. In addition, the antimicrobial properties of the cocrystal were investigated. The results of antimicrobial experiments revealed that cocrystal 1 inhibited Escherichia coli (E. coli) and Methicillin-resistant Staphylococcus aureus (MRSA). Molecular docking analysis unraveled the mode of interaction with DNA in bacteria. Cocrystal 1 is a potential multifunctional material for the preparation of TEA sensors and antimicrobial agents. Finally, the possible enhancing mechanism and potential antimicrobial mechanism were researched.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call