Abstract
Cytopathic Effect (CPE) refers to the structural changes of host cells caused by virus invasion. Infection with the virus causes the host cell to lyse, or when the cell dies because it cannot replicate. Both of these effects occur due to CPE. If the virus causes these morphological changes in the host cell, it is said to be cytopathic. Common examples of CPE include rounding of infected cells, fusion with neighboring cells to form syncytia, and the appearance of nuclear or cytoplasmic inclusions. EPC and other changes in cell morphology are just a few of the many effects of cytocidal viruses.
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