Abstract

Utilizing as-prepared hollow cuprous oxide (Cu2O) nanospheres, a simple nonenzymatic glucose amperometric sensor was fabricated. The structure and morphology of hollow Cu2O nanospheres were characterized by transmission electron microscopy (TEM) and X-ray diffraction (XRD). Electrocatalytic activity of Cu2O was investigated by cyclic voltammetry (CV) and chronoamperometry, exhibiting a direct for the oxidation of glucose in an alkaline medium at 0.6V. This constructing sensor was applied in detection of glucose with a detection limit of 0.41μM, a linear detection range from 1.25 to 37.5μM and with a high sensitivity of 2038.2μAmM−1cm−2. Due to superior catalytic performance and low cost of hollow Cu2O nanospheres, it shows great potential in applications for direct sensing of glucose.

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