Abstract
The present study aims the development of new S-heterocyclic azo dyes synthesized from 1, 3-benzothiazole-2-thiol with various amines by diazo-coupling method and their structures are established by physico-chemical techniques. The target molecules were screened for antimicrobial, antitubercular, anticancer, and molecular docking studies. These compounds have shown appreciable inhibitory effect against studied microbial strains. The in silico molecular docking study exposed the significant interaction properties of the azo compounds against target receptor RpsA and showed an appreciable binding affinity of −4.3 to −5.5 kcal/mol.
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