Abstract
AbstractA synthetic route for obtaining 1‐butoxy‐1,3,3‐triethoxy[1,3‐2H2]propane a stable diacetal of the malondialdehyde, is described. The synthesis involves the condensation of deuterated butylvinyl ether with deuterated triethyl orthoformate in the presence of montmorillonite clay K‐10. The deuteration of butyl vinyl ether was accomplished via the intermediary formation of a stannane derivative which was quantitatively metallated by n‐butyllithium and then treated with 2H2O. From the diacetal the 1,3‐dideuterated malondialdehyde was obtained by a short treatment with acid ion exchange resin.
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