Abstract
A human diploid fibroblast-like cell strain, TIG-1, which has normal female karyotype, was established and characterized. The average in vitro lifespan is 67 population doublings. Changes in surface area, contents of protein and DNA, doubling time, saturation density, the efficiency of cell attachment and the ability of cell proliferation in a colony were examined in the course of cellular aging in culture. Characteristics of G6PD and LDH were also determined. Hydrocortisone prolongs the lifespan of this cell strain when the hormone is added to the medium in physiological concentrations.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
