Abstract
ObjectiveTo study the coumarin from the seeds oil leavings of Xanthoceras sorbifolia. MethodsThe chemical constituents were isolated and purified by combination of silica gel, macroporous resin, Sephadex LH-20, and ODS column chromatography. Their structures were elucidated by spectral and chemical methods. The cytotoxicity of the new compound against 10 selected human cancer cell lines was assayed. ResultsFive comarins were isolated and identified as fraxetin-7-O-β-d-[6'-(3''‑hydroxyl‑3''- methylglutaryl)] glucopyranoside (1), fraxoside (2), fraxetin (3), scopoline (4), and esculetin (5), respectively. ConclusionCompound 1 is a new compound. Unfortunately, this compound exhibited no cytotoxicity with tested cell lines.
Published Version
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