Abstract

One new bergenin derivative, named 11-O-veratroylbergenin (1) along with five known bergenin derivatives, 11-O-(3′-O-methylgalloyl) bergenin (2), 11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from Ardisia gigantifolia Stapf. Their structures were established on the basis of spectroscopic analysis, especially by means of 1D, 2D-NMR and HR–ESIMS analyses. Compounds 2, 4 and 5 showed significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 9.7, 9.0 and 7.8 µmol L−1, respectively. They showed more antioxidant activity than the positive control vitamin C (EC50 = 28.3 µmol L−1).

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