Abstract
A new aurone (1), together with 5 known compounds (2-6), were isolated from EtOAc-soluble extract of the seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic methods. All compounds were evaluated for in vitro inhibitory activity against diacylglycerol acyltransferase (DGAT). Among them, compound 1 showed selective inhibitory activity on DGAT1 with IC50 value of 54.9 ± 1.4 µM.
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