A modern look at the therapy of mastitis in industrial animal husbandry

Abstract

Relevance. The work is devoted to the results of the use of Enroflon gel in clinical and subclinical mastitis in Holstein-Friesian cows. The purpose of our research was to determine the therapeutic efficacy of the drug for mastitis in lactating cows and to determine the residual amount of antibiotic in milk samples. Methods . The studies were carried out in JSC "Agrofirma Patrushi" of the Sverdlovsk Region and LLC "Lesnye Polyany" in the Moscow Region. Experienced groups of cows were injected with Enroflon gel, which contains two active ingredients: enrofloxacin and ketoprofen. The drug was developed by LLC VIK-Animal Health. The diagnosis of subclinical mastitis was made using an express diagnostic kit designed to determine the number of somatic cells in milk. When diagnosing clinical mastitis, the general condition of the animals, the presence of signs of inflammation of the mammary gland and changes in the organoleptic parameters of milk were taken into account. Milk samples for residual amounts of enrofloxacin were examined at the Milk Research Laboratory of the All-Union Research Institute of the Dairy Industry. Results . The use of Enroflon gel in the treatment of clinical and subclinical mastitis in cows provided a therapeutic effect of 72,7% and 73,3%, respectively. In laboratory studies of milk samples using the RANDOX matrix biochip technology, no enrofloxacin residues were found in the treated animals 72 hours after the last injection of the drug. The experimental groups were observed for 10 days.