Abstract

The dielectrophoresis (DEP) phenomena is a motion of uncharged polarizable particles in the direction of most field strength site within a non-uniform electric field. Unlike various techniques, the DEP is an effective technique for particles manipulation and separation of biological particles. The manipulation and separation of biological cells are necessary to various biomedical applications such as cell biology analysis, diagnostics, and therapeutics. The traveling-wave dielectrophoresis (twDEP) and levitation are major subcategories of electro-kinetic motions that are generated as a result of the interaction between a non-uniform electric field and polarizable particles. This article presents a model of an electrokinetic platform that has a working principle of dielectrophoresis phenomena and Printed Circuit Board (PCB) technology for separation of different sizes of biological particles such as microbeads (simulated biological cells) and the blood formed elements (platelets and red blood cells (RBCs)) using two configurations of microelectrodes (traveling and levitation).

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