A Mini Review on Application of Boron Neutron Capture Therapy in Cancer Treatment

Abstract

Nowadays, Cancer is undoubtedly a consequential and potentially life-threatening illness. In the U.S., Around 1.7 million people discerned with Cancer last year. The application of boron in cancer treatment is applicable as therapy known as Boron Neutron Capture Therapy (BNCT). It is an analeptic technique that depends on the nuclear capture and fission reaction that results in various particles such as Li, He nuclei with their kinetic energy and γ-radiation. These radiations kill the malignant cells in our body without damaging the normal tissue. Boron particles delivered selectively to only malignant cells by minimizing their concentration in normal cells.In this article, The clinical trials, clinical investigation in Different countries with a different type of Cancer as Lung, Brain, Head/Neck, Hepatic and gastrointestinal. Various delivery methods of Boron agents in the tumor cells recently developed boron delivery agents, and different techniques of their dose distribution explain. In recent years, boron compounds were applied with porphyrin, copolymers, nanoparticles, other peptides, EGRF’s, and Liposomes to intensify their killer properties toward target cancer cells. BNCT is also effectively used for the medication of various kinds of Cancers explained. The purpose of this article is to indicate the intelligible way of BNCT(Reactor-Based) for the treatment of malignant cells.