Abstract
A novel micro-coated wire trazodone-selective electrode placed in an FIP system is characterized and used to determine trazodone levels in various samples. The electrode is based on the immobilization of a PVC-sensing membrane, composed of a trazodone-tetraphenylborate ion-exchanger, on a platinum wire and incorporated in a novel miniaturized FIA-cell. The method provided a fast, stable and near-Nernstian response over a wide trazodone concentration range (5 × 10 −6 − 5 × 10 −3 M) with a mean slope of 53.9 ± 0.4 mV dec −1 of concentration and a mean detection limit of 4.4×10 −6 ±18×10 −7 M. The electrode also showed good repeatability, reproducibility and selectiv
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