A Meta-Analysis of Intervention Trials Examining the Effects of A Simple 2-Week Weight Loss Program on Body Weight and Waist Circumference

Abstract

Background: Relatively faster initial weight loss may enhance participant motivation to adhere to a longer-term weight reduction or maintenance plan and overall healthier lifestyle. The Special K Challenge TM is a portion-controlled, 2-week program that recommends replacement of two meals per day with ready-to-eat cereal and incorporation of portion-controlled snacks, fruits, and vegetables to help participants either begin a weight loss program or attain short-term weight loss for ongoing weight maintenance efforts. The objective of this meta-analysis is to examine the effects of a shortterm weight loss program on body weight and waist circumference in ten trials conducted across seven countries. Methods: Random effects meta-analyses generating weighted mean differences in body weight and waist circumference from baseline to 2-weeks (within-group analyses) and comparing intervention to control, where applicable. Results: The Special K Challenge TM intervention resulted in statistically significant weighted mean reductions in body weight (-1.61 kg, 95% CI: -1.85, -1.37) and waist circumference (-2.19 cm, 95% CI: -2.72, -1.66) in the within-group analyses. Compared to the control group, the Special K Challenge TM intervention resulted in a statistically significant decrease in body weight (-1.43 kg, 95% CI: -2.10, -0.76) and waist circumference (-1.20 cm, 95% CI: -2.20, -0.20). Two subgroups analyses, one among women only and one by readyto-eat-cereal serving size, were consistent with these findings. Conclusion: Overall, successful short-term weight loss was achieved, demonstrating that a simple, energy-reduced program with calorie-controlled meals and snacks is an effective approach to attain short-term weight loss and reduce waist circumference among overweight individuals.