Abstract
The involvement of kidney in marginal zone lymphoma is not a frequent condition. Seventy-seven-year-old female presented with renal failure. Renal biopsy revealed diffuse lymphoid infiltration replacing the normal renal tissue. Immunohistochemical staining was CD20, CD38, kappa, IgD positive and CD3, lambda, cyclin D1, CD5, CD23, CD43 negative. Ki-67 was 10% positive. The patient was diagnosed as MALT type marginal zone lympho-ma. Body Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) performed for staging revealed diffuse FDG uptake in both kidneys and no lym-phadenopathy was detected. Bone marrow aspiration and biopsy were normal. Rituximab - bendamustin chemotherapy regimen was started. In conclusion, this is the first case of MALT lymphoma involving kidney diffusely which requires rapid diagnosis and treatment to prevent irreversible loss of renal functions.
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