Abstract
This study aimed to develop a low-cost multichannel neural recording system and multi-electrode array (MEA)chip for a number of research laboratories. Because these elaborate systems may be cost-prohibitive for manylaboratories, the simple fabrication of the MEA chip and the construction of the low-cost recording systemwith cellular image acquisition is presented in this study. The MEA chip is a polyimide-based microelectrodearray with 60 electrodes (5 m thick, 30 m in radius and with 200 m spacing) and is based on the semi-conductor process and advanced microelectro-mechanical system (MEMS) technology. The three-dimensional(3D) structure of the electrodes is fabricated by electroplating, which produces rough textures that increasedthe effective surface area. The
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