Abstract
Virtual phantom simulation with Monte Carlo radiation transport codes is useful in patient-specific dosimetry, especially in molecular radiation therapy. The aim of this work was to get a conversion doses factor called S value in MIRD method using Monte Carlo simulation for estimate absorbed doses in kidney of 131I. it was considered the real anatomic structure, density and chemical composition of media and tissues from the abdominal region. The structural information was obtained from 24 computed tomography images in DICOM format and introduced in MCNPX 2.6. Results show a mass of 237.33 g of a whole kidney, which approximates the masses reported in the literature, the average S value in the kidney voxelized model was 2.26x10−05 mGy MBq−1 s−1 and an average deposited energy of 0.0335 MeV per 1 Bq of activity incorporated. In this case, average absorbed dose in the organ was estimated for the activities frequently used in molecular radiotherapy 50, 100, 150 and 200 mCi resulting in 6.73×1002 mGy, 1.35×1003 mGy, 2.03×1003 mGy and 2.71×1003 mGy respectively due to accumulation of 131I in the kidney. The average absorbed dose in the kidney got with the voxelized model was compared with the doses reported according to the OLINDA/EXM code, the publications MIRD 11, ICRP 53 and ICRP 80.
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