Abstract
ABSTRACTPreventive measures have helped to minimize the occurrence of dental caries. However, premature loss of primary teeth on account of dental caries still remains a common problem among children. The pulpotomy technique has been the choice for treating vital primary and young permanent teeth with carious, mechanical and traumatic pulp exposures. The ideal pulpotomy medicament should be bioinductive or at least biocompatible, bactericidal and harmless to the pulp and surrounding structures. It should also promote healing of the radicular pulp and prevent bacterial microleakage with the least interference in the physiological process of root resorption. Since the best criteria for judging the effectiveness of a medicament when used for vital pulp therapy is the response that it produces in the pulp. The purpose of the present study was to evaluate and compare the response of human pulp tissue to recently developed Indian material, Sree Chitra-Calcium Phosphate Cement (Chitra-CPC) and formocresol, used as pulpotomy agent in deciduous teeth. Chitra-CPC has been compared with formocresol, taking into account that formocresol is still considered the gold standard in primary tooth pulpotomy. The study was conducted among 10 children in the age group of 8 to 12 years focusing on 20 noncarious primary canines indicated for serial extraction. Each patient received two different pulpotomy procedures—one in each of the primary canines using formocresol and the other with Chitra-CPC as pulpotomy agents. After 70 days, the teeth were extracted and subjected to histological examination. The results did not reveal statistically significant difference between the two groups. But Chitra-CPC gave more favorable results, in respect of pulpal inflammation, dentin bridge formation, quality of dentin bridge and connective tissue in dentin bridge.How to cite this article: Ratnakumari N, Thomas B. A Histopathological Comparison of Pulpal Response to Chitra- CPC and Formocresol used as Pulpotomy Agents in Primary Teeth: A Clinical Trial. Int J Clin Pediatr Dent 2012;5(1):6-13.
Highlights
The ideal pulpotomy material or drug should be bioinductive or at least biocompatible, preserve healthy radicular pulp tissue, be bactericidal, be harmless to the pulp and surrounding structures, promote healing of the radicular pulp, prevent bacterial microleakage and should not interfere with the physiological process of root resorption.[10]
The International Agency for Research on Cancer (IARC) classified formaldehyde as carcinogenic to humans in June 2004, leaving the profession to look for other viable alternatives to formocresol.[12,18]
Since the best criteria for judging the effectiveness of a medicament when used for vital pulp therapy is the response it produces in the pulp, the present study evaluated the efficacy of Chitra-Calcium phosphate cement (CPC) as a pulpotomy agent in human deciduous teeth through histopathologic evaluation of pulpal response
Summary
The ideal pulpotomy material or drug should be bioinductive or at least biocompatible, preserve healthy radicular pulp tissue, be bactericidal, be harmless to the pulp and surrounding structures, promote healing of the radicular pulp, prevent bacterial microleakage and should not interfere with the physiological process of root resorption.[10] Formocresol is the most commonly used pulpotomy agent in deciduous teeth. It is a formaldehyde-cresol mixture and the rationale for its use is its bactericidal and pulpal fixative properties. The International Agency for Research on Cancer (IARC) classified formaldehyde as carcinogenic to humans in June 2004, leaving the profession to look for other viable alternatives to formocresol.[12,18]
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