Abstract
We designed and synthesized a highly selective and sensitive fluorescent probe for hydrogen sulfide (H2S) based on the one step nucleophilic addition reaction between H2S and electron-poor C=C double bond. Our proposed probe displayed high selectivity for H2S over other analytes including cysteine (Cys) and glutathione (GSH), which might be because the steric hindrance of H2S is less than other thiols. Additionally, a linear relationship between fluorescence intensity and the concentrations of Na2S (0-450 μM) was obtained in an aqueous buffer solution (pH 7.4, 20 mM PBS). Particularly, we found that the adoption of the acetyl benzimidazole derivative as a recognition receptor to distinguish H2S from other thiols and analytes provides a promising methodology for the design of fluorescent probes for the determination of H2S.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
