Abstract
A new dimension has been given to the Horner–Wadsworth–Emmons reaction almost 50 years after its inception. In an unprecedented vinylogous version of the reaction, aldehydes and cyano-substituted vinyl phosphonates serve as substrates (see scheme). The novel transformations to form 1,3-dienes with a trisubstituted double bond exhibit very high regio- and stereoselectivities.
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