Abstract
A very simple, non-destructive, inexpensive and green strategy applied for the quantification of Naproxen using transmission Fourier Transform Infrared (FTIR) spectroscopy in bulk & tablet dosage form and the Beer’s concentration range found to be 5-25μg. For the present investigation of Naproxen, O-H, 3000 - 3500cm-1 was selected for the analysis. The correlation coefficient for the method found to be 0.9965 and the developed method analyzed for specificity, limit of detection (LOD), limit of quantification (LOQ), linearity of response, precision and accuracy. This work clearly shows the capability of transmission FTIR spectroscopy for assessment of exact quantity of API to control the quality of finished products as well as during processing in pharmaceutical industries. Therefore, as compared to other spectroscopic or chromatographic method, costly chemicals and toxic solvents totally avoided in this direct, inexpensive and green approach. Such types of FTIR applications have a strong potential to replace classical methods in quality assurance /quality control (QA/QC) for the analysis of active contents in pharmaceutical preparations.
 Keywords: Accuracy; Beer’s law; Infrared spectroscopy; Limit of detection (LOD); Limit of Quantification; Naproxen
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Research in Pharmaceutical Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
