Abstract
Wireless capsule endoscopy (WCE) has been widely used in gastrointestinal (GI) diagnosis that allows the physicians to examine the interior wall of the human GI tract through a pain-free procedure. However, there are still several limitations of the technology, which limits its functionality, ultimately limiting its wide acceptance. Its counterpart, the wired endoscopic system is a painful procedure that demotivates patients from going through the procedure, and adversely affects early diagnosis. Furthermore, the current generation of capsules is unable to automate the detection of abnormality. As a result, physicians are required to spend longer hours to examine each image from the endoscopic capsule for abnormalities, which makes this technology tiresome and error-prone. Early detection of cancer is important to improve the survival rate in patients with colorectal cancer. Hence, a fluorescence-imaging-based endoscopic capsule that automates the detection process of colorectal cancer was designed and developed in our lab. The proof of concept of this endoscopic capsule was tested on porcine intestine and liquid phantom. The proposed WCE system offers great possibilities for future applicability in selective and specific detection of other fluorescently labelled cancers.
Highlights
The wireless capsule endoscopy (WCE) system is becoming increasingly popular for examining the entire human gastrointestinal (GI) tract, as this method eases patients’ discomfort and pain compared to other endoscopy methods [1]
The four printed circuit board (PCB) are connected via headers, and the design was selected as the best solution for the compact, efficient, and reliable design
WCE has enabled a pathway towards pain-free diagnosis and screening of the entire GI tract
Summary
The wireless capsule endoscopy (WCE) system is becoming increasingly popular for examining the entire human gastrointestinal (GI) tract, as this method eases patients’ discomfort and pain compared to other endoscopy methods [1]. There are still many challenges (such as image quality, frame rate, battery life, automatic detection of abnormalities, localization, etc.) associated with this promising technology, and these limit its use in modern day healthcare system [2,3]. These tiny swallowable capsules are designed to reach the areas where access is limited without performing surgery. After 24 h, the patient returns the data logger to the physician who downloads the images from the data logger to a computer, where the images are examined using the vendor’s software [7]. The software labels the frames suspected to include abnormalities, which would be examined by the physician [7]
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