Abstract
Abstract magnified imageA facile synthesis of tetrasubstitude 2,3‐dihydrofurans has been conducted using poly(ethylene glycol) (PEG) as a soluble polymer support. The PEG‐supported pyridinium ylides react with 3‐arylidene‐2,4‐pentanedione in the presence of triethylamine (TEA) via conjugate addition to form PEG‐supported dihydrofuran derivatives, being cleaved by 1% KCN/EtOH to afford trans‐tetrasubstitude‐2,3‐dihydrofurans, varying from good to excellent yields. J. Heterocyclic Chem., (2010).
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