Abstract
Abstract The electrochemical synthesis of some new sulfonamide derivatives was carried out via the electrochemical oxidation of 2,3-dihydrophthalazine-1,4-dione ( 1 ) in the presence of arylsulfinic acids ( 2a and 2b ) as nucleophiles. The results show that, the electrogenerated phthalazine-1,4-dione ( 1ox ) participates in a Michael type addition reaction with 2a or 2b and via an EC mechanism to produce the corresponding sulfonamide derivatives. This method provides a one-pot procedure for the synthesis of new sulfonamide derivatives of potential biological significance in good yields without using toxic reagents at a carbon electrode in an environmentally friendly manner.
Published Version
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