Abstract
β-Amino alcohols are bioactive molecules, used also as catalysts in asymmetric C–C bond formation. While asymmetric synthesis has been the preferred route for their preparation, there was always been a need to develop a facile methodology involving environmentally friendly transformations. Masked amines in the form of phthalimide alcohols, prepared via a fast coupling reaction in an ionic liquid as a reusable reaction media together with reduction and an efficient biocatalytic resolution, offer a green methodology for enantiomerically pure products (ee > 99%, 50 g L−1).
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call