A facile and scalable strategy for constructing Janus cotton fabric with persistent antibacterial activity

Abstract

Natural cotton fibers have attached considerable attention due to their excellent wearing comfort, breathability and warmth. However, it remains a challenge to devise a scalable and facile strategy to retrofit natural cotton fibers. Here, the cotton fiber surface was oxidized by sodium periodate with a mist process, then [2-(methacryloyloxy) ethyl] trimethylammonium chloride (DMC) was co-polymerized with hydroxyethyl acrylate (HA) to obtain an antibacterial cationic polymer (DMC-co-HA). The self-synthesized polymer was covalently grafted onto the aldehyde-functionalized cotton fibers via an acetal reaction between hydroxyl groups of the polymer and aldehyde groups of the oxidized cotton surface. Finally, the resulted Janus functionalized cotton fabric (JanCF) revealed robust and persistent antimicrobial activity. The antibacterial test showed that when the molar ratio of DMC/HA was 50: 1, JanCF possessed the best BR (bacterial reduction) values of 100 % against Escherichia coli and Staphylococcus aureus. Furthermore, the BR values could be maintained over 95 % even after the durability test. In addition, JanCF exhibited excellent antifungal activity against Candida albicans. The cytotoxicity assessment confirmed that JanCF exhibited a reliable safety effect on human skin. Particularly, the intrinsic outstanding characteristics (strength, flexibility, etc.) of the cotton fabric were not considerably deteriorated compared to the control samples.