Abstract

The work describes an efficient one-pot synthesis of 2,4,6-trisubstituted pyridine derivatives through a three-component catalytic reaction. The procedure involves mesoporous organic polymer based on calix[4]resorcinarene in and functionalized by N-propyl sulfamic acids a solid acid catalyst. Excellent yields, short reaction times, catalyst reusability, and easy reaction handling under solvent-free and mild acidic conditions are the most important advantages of the present protocol. The acidic catalyst was characterized by a number of spectroscopic methods such as Fourier-transform infrared spectroscopy, field emission scanning electron microscopy, transmission electron microscopy and elemental CHNS analysis.

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