Abstract
4,5-Dihydro-1H-2,5-benzoxazocine-1,6(3H)-diones have been synthesized by treatment of tert-butoxycarbonyl (Boc)-protected 1,2-cyclic sulfamidates with phthalic acid derivatives. Protection of one acid hydroxy group and the deprotection of the N-Boc group of the adducts, followed by cyclization, afforded the desired products in high yields. When derivatives of isophthalic acid were used in the synthetic sequence, nine-membered-ring analogues were formed. All the prepared compounds except one are novel.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call