Abstract
Postpartum hemorrhage is the leading cause of maternal mortality in India, accounting for 25---30% of all maternal deaths [1]. A large number of deliveries still occur at home, especially in rural areas. Injectable uterotonics are not necessarily applicable to these settings, as their effective use requires safe administration and special storage to maintain stability. In this prospective double blind randomized study conducted in 2005-06 at the Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, 200 women at low risk of PPH were randomized to receive either two tablets of misoprostol (400 mcg) sublingually or 1ml of methylergometrine (200 mcg) intramuscularly at the delivery of anterior shoulder of baby. Identical looking placebo tablets and injections were used. Primary and secondary outcomes measured are shown in Table 1. The duration of third stage, mean blood loss and need for additional oxytocics was similar in both
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More From: International Journal of Gynecology and Obstetrics
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