Abstract
Background: Post partumhemorrhage (PPH) is an important cause of maternal mortality accounting for nearly 15-20% of maternal deaths in India. Oxytocic drugs like oxytocin, ergot alkaloids, and various prostaglandins are being used for active management of third stage of labour. Materials and Methods: A prospective study was conducted in the Department of Obstetrics and Gynaecology of Al Ameen Medical College, Vijayapur, in 400 women. Patients were randomized into four groups of 100 each and were given oxytocic within 60 seconds of delivery anterior shoulder of the baby. Oxytocics used were 10 IU intramuscular oxytocin,125 µg intramuscular carboprost, 0.2 mg intravenous methylergometrine, and 800 µg tablet misoprostol per rectally in groups A, B, C and D respectively. Results: Duration of third stage of labor recorded was minimum with carboprost with mean duration of 3.84+/-0.99 minutes and was maximum with methylergometrine with mean duration of 5.04+/-1.02 minutes. Amount of blood loss observed was minimum with carboprost (mean 131 +/-72.037 ml) and maximum with Methylergometrine (mean 435+/-147.578 ml). Hemoglobin drop was also seen more with Methylergometrine with mean drop of 0.872+/-0.458 gm% and minimally with carboprost with mean drop of 0.236 +/-0.221 gm%. Conclusion: It is concluded from this study that carboprost is the uterotonic of choice followed by oxytocin for active management of third stage of labor.
Highlights
The third stage of labour is the most crucial stage, begins with expulsion of baby and ends with expulsion of placenta and membranes
Maximum blood loss was in patients given methylergometrine and minimal in patients given Carboprost with a p-value of
This study has shown that that carboprost is the uterotonic of choice followed by oxytocin for active management of third stage of labor
Summary
The third stage of labour is the most crucial stage, begins with expulsion of baby and ends with expulsion of placenta and membranes. Postpartum hemorrhage is one of the dreaded complications of third stage of labour. Post partumhemorrhage (PPH) is an important cause of maternal mortality accounting for nearly 15-20% of maternal deaths in India. Ergot alkaloids, and various prostaglandins are being used for active management of third stage of labour. Oxytocics used were 10 IU intramuscular oxytocin,125 μg intramuscular carboprost, 0.2 mg intravenous methylergometrine, and 800 μg tablet misoprostol per rectally in groups A, B, C and D respectively. Results: Duration of third stage of labor recorded was minimum with carboprost with mean duration of 3.84+/-0.99 minutes and was maximum with methylergometrine with mean duration of 5.04+/-1.02 minutes. Conclusion: It is concluded from this study that carboprost is the uterotonic of choice followed by oxytocin for active management of third stage of labor
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Obsgyne Review: Journal of Obstetric and Gynecology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
