Abstract
A diorganotin(IV) complex formulated as [(Me)2Sn(L)] (1) (H2L = 2,6-diacetylpyridine bis(N4-cyclohexylthiosemicarbazone) has been synthesized and structurally characterized by elemental analysis, IR, UV, and NMR spectroscopy, and single-crystal X-ray diffraction. Complex 1 contains mononuclear neutral molecules composed of one N3S2 pentadentate anionic thiosemicarbazone ligand and one (Me)2Sn(IV) group with a seven-coordinated tin ion. In vitro biological studies have indicated that complex 1 exhibited enhanced cytotoxicity compared to the thiosemicarbazone alone against human hepatocellular carcinoma HepG2 cells and could slightly distinguish HepG2 cells from normal hepatocyte QSG7701 cells.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.