Abstract

We present a debubbler for the removal of air bubbles in aqueous liquids in microfluidics. The debubbler is realized through an array of cylinder-shaped air-liquid interfaces, or air-pillars, formed directly into the microfluidic channels by surface tension. The debubbler demonstrated effective trapping and removal of both chemically generated bubbles (several nanoliters to several microliters in volume) and air slugs with several microliters in volume, which were formed by high infusion rates of bubble series introduced into the microchannel.

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