A Cytomorphometric study of Cervical Cancer and Pre-cancer in West Bengal with special reference to Midnapore district

Abstract

The purpose of this study was to measure some cytomorphometric parameters in different female uterine cervical conditions to study the progression of pathology from normal to neoplastic conditions. Using a computerised cytomorphometric cellmeasurement pro- gram, the study was based on a cross sectional study of smear cases diagnosed with different uterine cervical conditions from 2012 to 2014.From different kinds of microscopic image ( bright field microscopy), 100 pictures of normal cells and 100 pictures of pathological cells are selected. Then some cytoplasmic and nuclear parameters(Area, Perimeter, Convex area, Eccentricity, Major axis length, Minor axis length, Equivalent diameter) are assessed. All the parameters(Area,Convex area,perimeter,major axis length,minor axis length,equivalent diameter) are lowest in neoplasia,highest in hypertrophied cervix. Area and convex areas are lowest in hypertrophied cervix and neoplasia,highest in dysplasia.Perimeter,major axis length,equivalent diameters are lowest in hypertrophied cervix,highest in dysplasia.Minor axis length is lowest in neoplasia,highest in dysplasia.