A Cytomorphometric Analysis of Cervical Diseases And Neutrophilic Morphology With Special Reference to West Bengal

Abstract

The purpose of this study was to measure some cytomorphometric parameters in different female uterine cervical conditions to study the progression of pathology from normal to neoplastic conditions. Using a computerised cytomorphometry cell measurement pro- gram, the study was based on a cross sectional study of smear cases diagnosed with different uterine cervical conditions from 2014 to 2015.From different kinds of microscopic image (Differential Interference contrast, Phase contrast, bright field microscopy) 100 pictures of normal cells and 100 pictures of pathological cells are selected. Then some cytoplasmic and nuclear parameters(Area, Perimeter, Convex area, Eccentricity, Major axis length, Minor axis length, Equivalent diameter, Compactness, Mean RGB value, Minimum RGB value, Maximum RGB value, Standard deviation of RGB value, Entropy of RGB value, Cooc features (Stats, contrast, stats, correlation, stats, energy, stats, homogeneity) are assessed. Among the cytoplasmic features area is lowest in dysplasia and highest in neoplasia, major axis length is lowest in dysplasia and highest in hypertrophied cervix, minor axis length is lowest in dysplasia and highest in hypertrophied cervix, Equivalent diameter is lowest in cervicitis and highest in neoplasia. Among the nuclear features area is lowest in hypertrophied cervix and highest in neoplasia, major axis length is lowest in cervicitis and highest in neoplasia, minor axis length is lowest in cervicitis and highest in neoplasia, Equivalent diameter is lowest in cervicitis and highest in neoplasia. Areas,convex areas,minor axis lengths are lowest in normal conditions,highest in neoplasia.Perimeters,major axis lengths,equivalent diameters are lowest in nomal conditions,highest in cervicitis.It represents inflammatory reactions in neoplastic conditions.